TABLE 2

Phase I Dose-Escalation Trial with 177Lu-DOTA-J591

Dose levelPatients (n)177Lu-DOTA-J591
MBq/m2J591 (mg*/m2)
1337010
2355510
351,11010
451,66510
532,22010
662,59010
732,77510

  • ↵* 177Lu-DOTA-J591 (1–15 mg) was mixed with unlabeled J591 mAb to administer a total of 10 mg/m2 antibody mass.