TABLE 3

Comparison of 4 Methods for Estimating Red Marrow Dose

Patient no.Red marrow radiation-absorbed dose for 90Y-hMN-14 IgG (mGy/MBq)
Method 1*Method 2Method 3Method 4§
18271.081.271.461.19
18311.141.161.031.08
18890.971.241.301.11
  • * Blood and urine clearance data of 90Y-hMN-14 given in injection 2.

  • Blood and urine clearance of 111In-hMN-14 coadministered with 90Y-hMN-14 (second injection).

  • Blood and WB (scintigraphy) clearance based on 111In-hMN-14 given in first injection.

  • § Blood and WB (scintigraphy) clearance based on 111In-hMN-14 given in second injection.