Tumor-to-Tissue Ratios of 67Ga- and 177Lu-BZH3 in Tumor-Bearing Nude Mice
| Tumor/organ | 67Ga | 177Lu | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 1 h | 2 h | 4 h | 24 h | 1 h | 24 h | |||||
| Blood | 22.6 ± 2.4 | 38.1 ± 8.5 | 43.8 ± 11.7 | 140 ± 81 | 8.9 ± 1.5 | 59 ± 23 | ||||
| Liver | 12.0 ± 1.8 | 16.2 ± 1.8 | 16.4 ± 6.0 | 9.5 ± 2.3 | 7.3 ± 0.8 | 4.2 ± 1.0 | ||||
| Spleen | 1.7 ± 0.6 | 1.8 ± 0.6 | 2.3 ± 1.0 | 2.5 ± 0.7 | 2.7 ± 0.3 | 4.8 ± 1.3 | ||||
| Kidneys | 0.83 ± 0.05 | 1.4 ± 0.2 | 1.3 ± 0.4 | 1.2 ± 0.3 | 0.91 ± 0.28 | 2.1 ± 0.3 | ||||
| Pancreas | 0.13 ± 0.01 | 0.17 ± 0.04 | 0.14 ± 0.05 | 0.10 ± 0.02 | 0.14 ± 0.02 | 0.40 ± 0.10 | ||||
| Muscle | 74 ± 30 | 83 ± 26 | 131 ± 57 | 105 ± 28 | 34.8 ± 10.8 | 74 ± 39 | ||||
| Bone | 14.5 ± 0.8 | 22.3 ± 3.9 | 20.2 ± 1.7 | 10.5 ± 1.5 | 7.7 ± 0.6 | 1.9 ± 0.5 | ||||
| Lungs | 18.2 ± 3.1 | 34.1 ± 4.7 | 40.5 ± 15.0 | 52 ± 14 | 10.0 ± 1.5 | 30.7 ± 11.6 | ||||
Ratios are calculated from animals of Table 2. Data are mean ± SD (n = 5).