TABLE 4

Decrease of 18F-Fluoro-l-DOPA Uptake in Striatum of Patients with Multiple-Time Graphical and SPM Analysis, Compared with Control Group

PatientsMultiple-time graphical analysisSPM analysisP†
CaudatePutamenSubstantia nigra
CaudatePutamenP*x, y, zZ scorex, y, zZ score
Control0.0127 ± 0.00130.0117 ± 0.0010
All 350.0109 ± 0.00140.0105 ± 0.0016<0.001‡NS26, 12, −44.9−6, −24, −145.63<0.001
−22, 6, −44.7
Group 10.0103 ± 0.00130.0100 ± 0.0015<0.001‡NS26, 2, −44.47−8, 20, −144.81<0.001
−24, 6, −44.384, −32, −283.94
Group 20.0109 ± 0.00130.0105 ± 0.0019<0.001§NS32, 0, −23.45−2, −26, −165.08<0.001
<0.02‖−18, 12, −83.99
Group 30.0119 ± 0.00090.0114 ± 0.0010>0.05‡NS−28, −10, −23.0−8, −24, −103.59<0.005
2, −12, −143.18

  • ↵* ANOVA; patients vs. control subjects.

  • ↵† t test analysis; patients vs. control subjects.

  • ↵‡ For both nuclei.

  • ↵§ For caudate.

  • ↵‖ For putamen.

  • NS = not statistically significant.

  • Data are mean ± SD.