Biodistribution (%ID/g) of 67Ga-Complex 1b in Tumor-Bearing Nude Mice
| 5 min after injection | 60 min after injection | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Organ | %ID/g | Tissue-to-blood ratio | Organ | %ID/g | Tissue-to-blood ratio | ||||||||
| Average | Range | Average | Range | ||||||||||
| Blood | 0.99 | 0.02 | Blood | 0.08 | 0.01 | ||||||||
| Heart | 6.44 | 0.00 | 6.5 | Heart | 8.33 | 0.30 | 105 | ||||||
| KB3-1 | 0.31 | 0.05 | 0.3 | KB3-1 | 0.35 | 0.02 | 4.4 | ||||||
| KB8-5-11 | 0.21 | 0.02 | 0.2 | KB8-5-11 | 0.10 | 0.02 | 1.28 | ||||||
Biodistribution of 67Ga-complex 1b in blood, heart, and tumors of nude mice with subcutaneous KB3-1 and KB8-5-11 xenografts. Mice were injected intravenously with 74 kBq (2 μCi) of 67Ga-complex 1b and sacrificed at 5 or 60 min after injection; tissues were harvested and counted. Data are expressed as %ID/g tissue at each time point. Values represent mean ± range (n = 2). Also shown are tissue-to-blood ratios at each time point.