TABLE 3

Cumulative Absorbed Dose Calculations

Carrier system	⁹⁰Y			¹⁸⁸Re			³²P			¹³¹I			⁶⁷Cu
Carrier system		R (μm)	D_c/ D_max	R (μm)	D_c/ D_max	R (μm)	D_c/ D_max	R (μm)	D_c/ D_max	R (μm)	D_c/ D_max	R (μm)	D_c/ D_max	R (μm)	D_c/ D_max
MLV (DMPC:DC-chol)	16	0.62	16	0.62	16	0.65	14	0.55	14	0.52	14	0.05	12	0.04
MLV (DMPC:DOPE:DC-chol)	22	0.69	22	0.68	22	0.72	20	0.62	20	0.59	18	0.07	16	0.06
MLV (DMPC:DOPE:DOTAP)	32	0.71	32	0.70	32	0.75	32	0.66	30	0.64	24	0.09	22	0.09
SUV (DMPC-chol)	46	0.93	44	0.92	48	0.95	42	0.92	42	0.91	28	0.40	26	0.38
SUV (DMPC:DC-chol)	18	0.58	18	0.56	18	0.61	18	0.52	18	0.49	16	0.04	16	0.04
SUV (DMPC:DOPE:DC-chol)	20	0.61	20	0.60	20	0.63	20	0.53	20	0.50	20	0.07	18	0.05
SUV (DMPC:DOPE:DOTAP)	44	0.87	44	0.86	44	0.90	42	0.84	40	0.82	28	0.28	26	0.25
Antibody J591	20	0.84	20	0.85	20	0.84	20	0.84	16	0.85	4	0.42	0	0.52

R refers to distance from rim of spheroid where absorbed dose is maximum (D_max); D_c was calculated at core of spheroid, which was at 100-μm depth for liposome experiments and 80-μm depth for antibody.