Administered Activities, Typical Response Times and Duration, and Retreatment Intervals for Bone-Seeking Radionuclides
| Radiopharmaceutical | Usual administered activity | Typical response time | Typical response duration | Retreatment interval |
|---|---|---|---|---|
| 32P | 444 MBq [fractionated] | 14 d | 10 wk | >3 mo |
| 89SrCl2 | 148 MBq | 14–28 d | 12–26 wk | >3 mo |
| 186Re-HEDP | 1.3 GBq | 2–7 d | 8–10 wk | >2 mo |
| 188Re-HEDP | 1.3–4.4 GBq | 2–7 d | 8 wk | NE |
| 153Sm-EDTMP | 37 MBq/kg | 2–7 d | 8 wk | >2 mo |
| 117mSn-DTPA | 2–10 MBq/kg | 5–19 d | 12–16 wk | >2 mo |
| 223RaCl2 | 50–200 kBq/kg | <10 d | NE | NE |
NE = not established.