Scoring of Adverse Events According to Common Toxicity Criteria, Version 2.0
| Session | Adverse event | Grade | Attribution to investigational agent |
|---|---|---|---|
| 1 | Fatigue (day 2) | 2 | Possibly |
| Increase in bilirubine (week 2) | 3 | Possibly | |
| Increase in AST (day 2 to week 2) | 2 | Possibly | |
| 3a | Colitis (week 2) | 2 | Unlikely |
| 4 | Diarrhea (day 2) | 1 | Unrelated |
| Tumor pain (week 2) | 1 | Possibly | |
| 6a | Infection with fever (week 2) | 2 | Unlikely |
| Leukopenia (week 6) | 2 | Probably | |
| Thrombocytopenia (week 6) | 2 | Probably | |
| Cough (week 6) | 2 | Possibly | |
| 6b | Leukopenia (week 6) | 1 | Probably |
| Thrombocytopenia (week 6) | 3 | Probably | |
| Cough, dyspnea, pulmonary fibrosis (week 6) | 2 | Possibly | |
| Reduced carbon monoxide diffusion capacity | 3 | Possibly | |
| 7c | Tumor pain (week 2) | 1 | Possibly |
| 8 | Fatigue (week 2) | 2 | Possibly |
| 9 | Fatigue (week 2) | 2 | Probably |
| Increase in AST (week 2) | 2 | Probably | |
| 10 | Infection with fever (days 2–7) | 1 | Unrelated |