TABLE 2

Radiation-Absorbed Dose Estimates from 153Sm-EDTMP in Tibias of 8-Week-Old Male New Zealand White Rabbits

TissuemGy/MBq (rad/mCi)
Proximal epiphysis141 (522)
Proximal physis50.0 (185)
Proximal metaphysis 1144 (534)
Proximal metaphysis 239.4 (146)
Diaphysis17.4 (64.5)
Red marrow5.38 (19.9)
Distal metaphysis 188.2 (327)
Distal metaphysis 242.0 (155)
Distal physis39.2 (145)
Distal epiphysis43.4 (161)
  • Metaphysis 1 compartment = 3 mm of tissue directly adjacent to physis, corresponding to maximum range of 153Sm β-particle in hard tissue; metaphysis 2 = remainder of tissue.