Results for 23 Patients Undergoing PET and MRI
| Patient no. | Tumor volume (cm3) as determined by … | Normalized tumor volume | Radiotracer uptake ratio* | SUV | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 18F-FLT | 11C-MET | MRI-Gd | FLT/Gd | MET/Gd | MET/FLT | 18F-FLT | 11C-MET | 18F-FLT | 11C-MET | |||||||
| 1 | 5.0 | 7.6 | — | — | — | 1.5 | 2.4 | 1.6 | 1.1 | 2.5 | ||||||
| 2 | 27.4 | 27.5 | 6.8 | 4.0 | 4.0 | 1.0 | 7.9 | 3.3 | 1.7 | 3.6 | ||||||
| 3 | 7.9 | 18.5 | — | — | — | 2.3 | 4.4 | 2.7 | 1.0 | 3.1 | ||||||
| 4 | 91.2 | 52.7 | 20.5 | 4.5 | 2.6 | 0.6 | 9.3 | 2.7 | 2.7 | 5.4 | ||||||
| 5 | 46.6 | 46.0 | — | — | — | 1.0 | 7.0 | 3.5 | 1.3 | 3.3 | ||||||
| 6 | 0 | 5.7 | 1.2 | 0 | 4.9 | — | (1.0) | 1.6 | (0.2) | 1.9 | ||||||
| 7 | 60.4 | 51.8 | 37.8 | 1.6 | 1.4 | 0.9 | 6.4 | 2.6 | 1.2 | 3.4 | ||||||
| 8 | 42.7 | 66.3 | — | — | — | 1.6 | 6.9 | 2.7 | 1.5 | 3.3 | ||||||
| 9 | 7.7 | 35.3 | 2.6 | 3.0 | 13.7 | 4.6 | 3.8 | 2.4 | 1.4 | 2.8 | ||||||
| 10 | 8.3 | 1.0 | 3.3 | 2.5 | 0.3 | 0.1 | 3.7 | 1.2 | 0.7 | 1.6 | ||||||
| 11 | 5.5 | 3.7 | 1.6 | 3.3 | 2.2 | 0.7 | 3.3 | 1.4 | 1.8 | 4.2 | ||||||
| 12 | 8.9 | 20.6 | — | — | — | 2.3 | 2.1 | 1.7 | 0.5 | 2.4 | ||||||
| 13 | 3.9 | 42.6 | 0.1 | 29.9 | 327.8 | 11.0 | 1.3 | 2.3 | 0.5 | 3.2 | ||||||
| 14 | 40.0 | 35.6 | 14.4 | 2.8 | 2.5 | 0.9 | 13.0 | 4.7 | 3.0 | 3.9 | ||||||
| 15 | 0 | 0 | 0 | — | — | — | (1.0) | (1.0) | (0.2) | (1.0) | ||||||
| 16 | 0 | 18.8 | — | — | — | — | (1.0) | 2.0 | (0.4) | 2.6 | ||||||
| 17 | 7.7 | 14.3 | 5.5 | 1.4 | 2.6 | 1.9 | 3.9 | 2.3 | 1.4 | 4.0 | ||||||
| 18 | 0.4 | 20.6 | 1.1 | 0.4 | 19.4 | 46.8 | 2.0 | 1.3 | 0.8 | 2.6 | ||||||
| 19 | 17.4 | 24.7 | 6.8 | 2.6 | 3.6 | 1.4 | 3.5 | 1.9 | 0.6 | 2.0 | ||||||
| 20 | 1.7 | 28.0 | — | — | — | 16.3 | 2.0 | 2.7 | 0.5 | 3.1 | ||||||
| 21 | 0 | 14.6 | 0 | — | — | — | (1.0) | 1.8 | (0.3) | 4.3 | ||||||
| 22 | 0 | 0 | 0 | — | — | — | (1.0) | (1.0) | (0.2) | (1.0) | ||||||
| 23 | 14.7 | 34.4 | 10.7 | 1.4 | 3.2 | 2.3 | 4.7 | 2.1 | 1.3 | 1.3 | ||||||
| Mean | 18.9 | 27.1 | 8.0 | 4.4 | 29.9 | 5.4 | 4.9 | 2.3 | 1.3 | 3.1 | ||||||
| SD | 24.2 | 17.6 | 10.4 | 7.8 | 89.7 | 11.1 | 3.0 | 0.8 | 0.7 | 1.0 | ||||||
↵* Calculated by dividing circular ROIs placed over tumor tissue by circular ROIs placed over intact brain. Uptake ratios of false-negative tumors in either PET examination were set to 1.