Characteristics of 22 Patients with Glioma and 1 Patient with Medulloblastoma
| Patient no. | Age (y) | Sex | Tumor type and WHO grade | Location | Side | ND/REC | Therapy before study entry | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Surgery | Radiation (Gy) | Chemotherapy | |||||||||
| 1 | 33 | F | Astrocytoma II | Frontal | R | REC | 1 | 54 | — | ||
| 2 | 59 | F | Glioblastoma IV | Temporal | L | REC | 2 | 60 | TMZ | ||
| 3 | 51 | F | Astrocytoma II | Precentral | R | REC | 1 | — | — | ||
| 4 | 49 | F | Glioblastoma IV | Temporal | L | REC | 1 | 60 | TMZ 5C | ||
| 5 | 70 | M | Glioblastoma IV | Frontoparietal | R | ND | — | — | — | ||
| 6 | 50 | F | Astrocytoma II | Frontotemporal | L | REC | 1 | — | — | ||
| 7 | 64 | M | Glioblastoma IV | Frontal | R | ND | — | — | — | ||
| 8 | 67 | M | Glioblastoma IV | Parietooccipital | L | ND | — | — | — | ||
| 9 | 39 | F | Astrocytoma III | Brainstem, thalamus | L | REC | — | 60 | TMZ 4C, PCV 5C | ||
| 10 | 35 | F | Glioblastoma IV | Temporal | R | REC | 2 | 60 | TMZ | ||
| 11 | 20 | M | Medulloblastoma IV | Cerebellar | R | REC | 2 | 3× | HIT-91, 97, 3× | ||
| 12 | 38 | M | Astrocytoma III | Parietooccipital | L | REC | 1 | 60 | PCV 2C | ||
| 13 | 57 | F | Oligoastrocytoma II | Thalamus | R and L | REC | 3 | 60 | — | ||
| 14 | 58 | F | Ganglioglioma III | Temporoparietal | L | REC | — | — | PCV 1C | ||
| 15 | 34 | M | Astrocytoma II | Precentral | L | ND | — | — | — | ||
| 16 | 38 | M | Astrocytoma II | Temporoparietal | L | REC | 1 | — | TMZ 9C | ||
| 17 | 26 | F | Astrocytoma I | Occipital | R | ND | — | — | — | ||
| 18 | 47 | F | Oligoastrocytoma III | Parietal | L | REC | 1 | 60 | TMZ | ||
| 19 | 33 | M | Astrocytoma III | Frontoparietal | R | REC | 1 | — | PCV 4C | ||
| 20 | 55 | M | Oligoastrocytoma II | Temporoparietooccipital | L | REC | 1 | — | — | ||
| 21 | 60 | F | Oligodendroglioma III | Parietal | L | ND | — | — | — | ||
| 22 | 31 | M | Astrocytoma II | Temporoparietal | L | ND | — | — | — | ||
| 23 | 69 | M | Astrocytoma II | Occipital | R | ND | — | — | — | ||
ND = newly diagnosed; REC = recurrent; TMZ = temozolomide; PCV = procarbazine, lomustine, and vincristine; HIT = randomized, prospective, multicenter trial in order to improve the survival of children with medulloblastoma by using postoperative neoadjuvant chemotherapy before radiation therapy as opposed to maintenance chemotherapy after immediate postoperative radiotherapy.