Biodistribution of 18F-FBPA in Tumor (T), Ipsilateral Brain (IB), Contralateral Brain (CB), and Blood (Bd) of F98 Glioma-Bearing Fischer 344 Rats at 0.5, 2.5, and 4.0 Hours after Intracarotid Administration of 18F-FBPA (29.6 MBq/kg of BW) with BBB-D
| Time (h) | Accumulation (%ID/g) | Ratio | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T | IB | CB | Bd | T/IB | T/CB | T/Bd | ||||||
| 0.5 | 3.32 ± 0.92 | 1.15 ± 0.44 | 0.87 ± 0.20 | 1.72 ± 0.15 | 2.9 | 3.8 | 1.9 | |||||
| 2.5 | 2.63 ± 0.72 | 0.55 ± 0.21 | 0.46 ± 0.12 | 0.39 ± 0.08 | 4.8 | 5.7 | 6.7 | |||||
| 4.0 | 1.48 ± 0.25 | 0.42 ± 0.08 | 0.24 ± 0.04 | 0.18 ± 0.06 | 3.5 | 5.9 | 7.9 | |||||
Each point represents mean ± SD of 4 or 5 rats. Rats were under isoflurane anesthesia.