Univariate and Multivariate Predictors of Cardiac Death or Myocardial Infarction
Parameter | Univariate | Multivariate | ||||||
---|---|---|---|---|---|---|---|---|
Clinical data | Model 1 | Model 2 | Model 3 | |||||
Clinical characteristics | ||||||||
Male patient | 1.8 (0.9–3.6) | NS | NS | NS | NS | |||
Previous infarction | 1.5 (0.7–2.9) | NS | NS | NS | NS | |||
Diabetes mellitus | 2.6 (1.2–5.5) | 2.6 (1.3–5.1) | 2.6 (1.3–5.2) | 2.3 (1.1–4.8) | 2.2 (1.1–4.5) | |||
Hypertension | 1.3 (0.6–2.5) | NS | NS | NS | NS | |||
Hypercholesterolemia | 0.9 (0.4–1.9) | NS | NS | NS | NS | |||
Smoking | 3.3 (1.6–6.9) | 2.5 (1.3–4.8) | 2.1 (1.1–4.1) | 2.7 (1.4–5.2) | NS | |||
Heart failure | 3.0 (1.3–6.7) | 3.0 (1.5–6.0) | 3.2 (1.6–6.4) | 2.6 (1.3–5.5) | 2.6 (1.3–5.4) | |||
Left bundle branch block | 3.7 (1.2–11) | NS | NS | NS | NS | |||
Stress test results | ||||||||
Angina pectoris | 1.2 (0.6–2.6) | — | NS | NS | NS | |||
ST-segment changes | 1.0 (0.5–2.1) | — | NS | NS | NS | |||
Peak heart rate | 0.8 (0.2–3.6) | — | NS | NS | NS | |||
Scan parameters | ||||||||
Abnormal findings | 7.8 (2.7–23) | — | 9.0 (2.8–30) | — | — | |||
Fixed defect | 3.2 (1.5–6.8) | — | — | 2.9 (1.5–5.8) | — | |||
Reversible defect | 2.7 (1.3–5.5) | — | — | 3.9 (2.0–7.7) | — | |||
Summed stress score/10 | 15.1 (5.3–47) | — | — | — | 13.1 (4.1–42) | |||
Total χ2 | 27 | 45 | 51 | 36 | ||||
Incremental value over clinical data | P < 0.0001 | P < 0.0001 | P < 0.001 |
NS = not significant; — = variable excluded.
Data are Cox proportional hazard ratio, with 95% confidence interval in parentheses. In model 1, the variable entered was the presence of an abnormal scan; in model 2, the presence of a fixed or reversible defect was entered; in model 3, the summed stress score was entered.