Univariate and Multivariate Predictors of Cardiac Death
| Parameter | Univariate | Multivariate | ||||||
|---|---|---|---|---|---|---|---|---|
| Clinical data | Model 1 | Model 2 | Model 3 | |||||
| Clinical characteristics | ||||||||
| Male patient | 1.0 (0.5–2.1) | NS | NS | NS | NS | |||
| Previous infarction | 1.1 (0.5–2.4) | NS | NS | NS | NS | |||
| Diabetes mellitus | 3.1 (1.3–7.1) | 2.9 (1.4–6.1) | 2.8 (1.3–6.3) | 2.6 (1.2–6.0) | 2.7 (1.2–5.9) | |||
| Hypertension | 1.6 (0.7–3.5) | NS | NS | NS | NS | |||
| Hypercholesterolemia | 0.9 (0.4–2.1) | NS | NS | NS | NS | |||
| Smoking | 3.1 (1.4–7.1) | 2.4 (1.1–5.0) | 2.3 (1.1–5.2) | 2.8 (1.3–6.1) | NS | |||
| Heart failure | 4.0 (1.7–9.4) | 3.4 (1.6–7.4) | 3.5 (1.6–7.7) | 2.8 (1.3–6.4) | 3.1 (1.4–6.8) | |||
| Left bundle branch block | 5.3 (1.7–16) | NS | 3.2 (1.3–8.3) | 3.0 (1.2–7.7) | NS | |||
| Stress test results | ||||||||
| Angina pectoris | 0.8 (0.3–2.1) | — | NS | NS | NS | |||
| ST-segment changes | 1.2 (0.5–2.7) | — | NS | NS | NS | |||
| Peak heart rate | 1.1 (0.2–5.0) | — | NS | NS | NS | |||
| Scan parameters | ||||||||
| Abnormal findings | 11.8 (2.7–51) | — | 12.1 (2.9–52) | — | — | |||
| Fixed defect | 3.2 (1.3–7.4) | — | — | 3.1 (1.5–6.8) | — | |||
| Reversible defect | 3.5 (1.6–7.7) | — | — | 4.5 (2.1–9.6) | — | |||
| Summed stress score/10 | 6.7 (2.1–22) | — | — | — | 6.7 (2.0–23) | |||
| Global χ2 | 25 | 47 | 53 | 28 | ||||
| Incremental value over clinical data | P < 0.0001 | P < 0.0001 | P < 0.05 | |||||
NS = not significant; — = variable excluded.
Data are Cox proportional hazard ratio, with 95% confidence interval in parentheses. In model 1, the variable entered was the presence of an abnormal scan; in model 2, the presence of a fixed or reversible defect was entered; in model 3, the summed stress score was entered.