Biodistribution (%ID/g) at 180 Minutes of 18F-FMISO and 18F-FAZA in Swiss Nude Mice Bearing A431 Tumor
| Tissue | 18F-FMISO (n = 7) | 18F-FAZA (n = 11) |
|---|---|---|
| Blood | 0.74 ± 0.16 | 0.31 ± 0.12 |
| Heart | 0.85 ± 0.46 | 0.61 ± 0.25 |
| Lung | 1.01 ± 0.56 | 0.38 ± 0.21 |
| Liver | 3.26 ± 2.00 | 1.23 ± 0.63 |
| Spleen | 0.66 ± 0.26 | 0.31 ± 0.14 |
| Kidney | 1.54 ± 0.99 | 0.65 ± 0.37 |
| Brain | 0.51 ± 0.21 | 0.56 ± 0.22 |
| Muscle | 1.05 ± 0.48 | 0.38 ± 0.16 |
| Bone | 1.77 ± 1.77 | 0.50 ± 0.17 |
| Skin | 1.00 ± 0.52 | 0.71 ± 0.85 |
| Stomach | 1.40 ± 0.72 | 0.64 ± 0.31 |
| Small intestine | 1.43 ± 0.77 | 0.90 ± 0.52 |
| Large intestine | 7.73 ± 4.00 | 1.63 ± 1.07 |
| Tumor | 3.67 ± 1.00 | 2.96 ± 1.27* |
| T/Bl ratio | 4.92 ± 0.77 | 9.62 ± 1.44† |
| T/M ratio | 3.95 ± 1.34 | 7.81 ± 0.94† |