In Vitro Stability of 111In-hnTf-VEGF Incubated with Human Plasma
| Time (h) | 111In transchelated to transferrin from 111In-hnTf-VEGF* (%) |
|---|---|
| 0.25 | 2.8 ± 1.3 |
| 4 | 10.0 ± 0.4 |
| 24 | 27.9 ± 0.5 |
| 48 | 46.5 ± 5.2 |
| 72 | 63.9 ± 2.3 |
↵* Values are mean ± SE for triplicate determinations. 111In-hnTf-VEGF was incubated with human plasma at 37°C for the specified times and the percentage transchelation to transferrin was measured by size-exclusion HPLC.