Performance of 18F-FDG PET and CT for Lymph Node Staging
| Type of cancer | Stage | Imaging type | Sensitivity | Specificity | Accuracy | PPV | NPV |
|---|---|---|---|---|---|---|---|
| Both EGC and AGC | N1 | PET | 34% (18/53) | 96% (27/28) | 56% (45/81) | 95% (18/19) | 44% (27/62) |
| CT | 58% (31/53) | 89% (25/28) | 69% (56/81) | 91% (31/34) | 53% (25/47) | ||
| N2 | PET | 34% (11/32) | 96% (47/49) | 72% (58/81) | 85% (11/13) | 69% (47/68) | |
| CT | 44% (14/32) | 86% (42/49) | 69% (56/81) | 67% (14/21) | 70% (42/60) | ||
| N3 | PET | 50% (3/6) | 99% (74/75) | 95% (77/81) | 75% (3/4) | 96% (74/77) | |
| CT | 50% (3/6) | 99% (74/75) | 95% (77/81) | 75% (3/4) | 96% (74/77) | ||
| EGC only (n = 17) | N1 | PET | 33%(1/3) | 100%(14/14) | 88%(15/17) | 100%(1/1) | 88%(14/16) |
| CT | 33% (1/3) | 100% (14/14) | 88% (15/17) | 100% (1/1) | 88% (14/16) | ||
| N2 | PET | 0% (0/2) | 100% (15/15) | 88% (15/17) | 88% (15/17) | ||
| CT | 0% (0/2) | 100% (15/15) | 88% (15/17) | 88% (15/17) | |||
| N3 | PET | 100% (17/17) | 100% (17/17) | 100% (17/17) | |||
| CT | 100% (17/17) | 100% (17/17) | 100% (17/17) | ||||
| AGC only (n = 64) | N1 | PET | 34% (17/50) | 93% (13/14) | 47% (30/64) | 94% (17/18) | 28% (13/46) |
| CT | 60% (30/50) | 79% (11/14) | 64% (41/64) | 91% (30/33) | 35% (11/31) | ||
| N2 | PET | 37% (11/30) | 94% (32/34) | 67% (43/64) | 85% (11/13) | 63% (32/51) | |
| CT | 47% (14/30) | 79% (27/34) | 64% (41/64) | 67% (14/21) | 63% (27/43) | ||
| N3 | PET | 50% (3/6) | 98% (57/58) | 94% (60/64) | 75% (3/4) | 95% (57/60) | |
| CT | 50% (3/6) | 98% (57/58) | 94% (60/64) | 75% (3/4) | 95% (57/60 |