TABLE 2

Comparison of Compartmental Model and Patlak Estimates of K_i, With and Without Intercept Correction, and TPR

Group	CM K_i	Patlak K_i	CM K_i/Int	Patlak K_i/Int	CM Int	Patlak Int	TPR
Normal	0.0014 ± 0.0005	0.0016 ± 0.0004	0.0077 ± 0.0029	0.0091 ± 0.0015	0.19 ± 0.04	0.18 ± 0.03	0.33 ± 0.06
OA	0.0023 ± 0.0006	0.0034 ± 0.0008	0.0090 ± 0.0049	0.0144 ± 0.0039	0.31 ± 0.11*	0.24 ± 0.04	0.62 ± 0.13
Etx	0.0078 ± 0.0027*	0.0079 ± 0.0026*	0.0308 ± 0.0100*^†	0.0319 ± 0.0086*	0.26 ± 0.07	0.25 ± 0.09	1.72 ± 0.68*
Etx+OA	0.0085 ± 0.0055*	0.0093 ± 0.0048*^†	0.0217 ± 0.0153	0.0213 ± 0.0107*	0.43 ± 0.11*^†^‡	0.44 ± 0.07*^†^‡	2.17 ± 1.48*

↵* P < 0.05 compared with normal group.
↵^† P < 0.05 compared with OA group.
^‡ P < 0.05 compared with Etx group.
CM = compartmental model.
Units for K_i are mL blood/mL lung/min; units for intercept and TPR are mL blood/mL lung.