TABLE 1

Compartmental Model Rate Constants

Group	K₁	k₂	k₃
Normal	0.0049 ± 0.0020	0.070 ± 0.058	0.028 ± 0.018
OA	0.0115 ± 0.0024	0.055 ± 0.035	0.014 ± 0.009
Etx	0.0149 ± 0.0068	0.040 ± 0.018	0.049 ± 0.031*
Etx+OA	0.0339 ± 0.0071*^†	0.081 ± 0.038	0.026 ± 0.016^‡

↵* P < 0.05 compared with OA group.
↵^† P < 0.05 compared with normal group.
↵^‡ P < 0.05 compared with Etx group.
CM = compartmental model.
Units for K₁ are mL blood/mL lung/min; units for other rate constants are min⁻¹.