TABLE 3

SUV_max, Ki-PAT, Ki-NLR, and Rate Constants in Pagetic and Normal Bones

Parameter	Pagetic bones					Normal bones
Parameter			Baseline	1 mo	6 mo	Baseline	1 mo	6 mo
SUV_max	35.07* ± 23.86	25.02*^† ± 20.42	18.49*^† ± 14.16	7.15 ± 4.76	6.43 ± 3.50	6.87 ± 3.70
Ki-PAT (mL/min/mL)	0.114* ± 0.115	0.083*^† ± 0.093	0.061*^† ± 0.062	0.014 ± 0.008	0.015 ± 0.008	0.016 ± 0.008
Ki-NLR (mL/min/mL)	0.127* ± 0.127	0.093*^† ± 0.104	0.066*^† ± 0.068	0.016 ± 0.009	0.017 ± 0.009	0.019 ± 0.010
K₁ (mL/min/mL)	0.164* ± 0.136	0.126*^† ± 0.115	0.087^† ± 0.077	0.037 ± 0.024	0.037 ± 0.022	0.047 ± 0.030
k₂ (min⁻¹)	0.119 ± 0.148	0.152 ± 0.177	0.063* ± 0.068	0.203 ± 0.178	0.158 ± 0.133	0.271^† ± 0.172
k₃ (min⁻¹)	0.198 ± 0.137	0.365 ± 0.317	0.319 ± 0.474	0.137 ± 0.075	0.213 ± 0.327	0.196 ± 0.125
k₄ (min⁻¹)	0.010 ± 0.010	0.012 ± 0.010	0.008 ± 0.008	0.015 ± 0.032	0.018 ± 0.030	0.017 ± 0.030
Ki-NLR/K₁	0.718* ± 0.181	0.722* ± 0.162	0.726* ± 0.153	0.387 ± 0.191	0.415 ± 0.181	0.401 ± 0.223

↵* Statistically different from normal control bone (P < 0.05).
↵^† Statistically different from previous time point (e.g., 1 mo vs. baseline) (P < 0.05).
Results are presented as mean ± SD.