TABLE 3

Quality-of-Life Assessments

Dimension	Control			DMR			VEGF
Dimension		Baseline	3 mo	Baseline	3 mo	Baseline	3 mo
RAND-36
Physical functioning	23	34*	36	58*	23	44*
Social functioning	40	40	57	65	25	52*
Role limitation physical	0	0	8	35*	4	25
Role limitation emotional	20	0	50	78	29	43
Mental health	51	41	59	66	49	60*
Vitality	34	41	38	55*	24	46*
Bodily pain	29	33	40	61*	26	57*
General health perception	27	31	31	47*	26	36
Perceived change in health	20	20	33	69	13	63*
MPVH, feelings of disability	34	35	34	31*	35	30*
MFI, fatigue overall score	77	75	71	58*	79	70*

↵* Large changes in dimension according to effect sizes proposed by Cohen (19,20) (≥0.80) are indicated.