TABLE 4

Percentage Increase in PET Parameters After PVC

Region	K*					V_b					CBF
Region		Young	Old	P	Young	Old	P	Young	Old	P
2S-PVC
Frontal	19 ± 9	27 ± 8	0.082	18 ± 8	24 ± 7	0.1	16 ± 7	24 ± 6	0.056
Temporal	13 ± 6	18 ± 7	0.1	13 ± 6	19 ± 4	0.041*	11 ± 6	17 ± 4	0.042*
Parietal	23 ± 9	32 ± 10	0.080	21 ± 8	32 ± 9	0.038*	20 ± 8	27 ± 7	0.081
Occipital	13 ± 6	19 ± 9	0.2	13 ± 6	16 ± 7	0.4	11 ± 6	15 ± 8	0.3
Caudate	13 ± 3	18 ± 6	0.051	12 ± 3	16 ± 4	0.1	12 ± 2	16 ± 4	0.029*
Putamen	0 ± 1	1 ± 1	0.1	0 ± 1	1 ± 2	0.2	0 ± 1	1 ± 1	0.13
Thalamus	6 ± 1	8 ± 2	0.018*	7 ± 2	9 ± 1	0.006*	5 ± 1	7 ± 1	0.011*
Cerebellum	9 ± 9	10 ± 5	0.7	10 ± 10	14 ± 6	0.4	9 ± 14	9 ± 4	0.9
Gray matter	16 ± 6	21 ± 7	0.2	15 ± 6	20 ± 5	0.091	14 ± 6	18 ± 5	0.2
3S-PVC
Frontal	54 ± 14	64 ± 19	0.2	37 ± 12	52 ± 13	0.036*	55 ± 11	63 ± 13	0.2
Temporal	43 ± 9	48 ± 11	0.3	34 ± 8	48 ± 7	0.004*	45 ± 7	49 ± 6	0.3
Parietal	67 ± 18	86 ± 22	0.1	48 ± 15	72 ± 11	0.005*	67 ± 16	85 ± 17	0.054
Occipital	54 ± 10	69 ± 17	0.1	42 ± 6	60 ± 13	0.004*	55 ± 8	68 ± 11	0.022*
Caudate	34 ± 4	36 ± 11	0.6	26 ± 4	31 ± 9	0.2	36 ± 5	37 ± 9	0.8
Putamen	35 ± 6	30 ± 9	0.2	20 ± 7	26 ± 6	0.071	39 ± 7	35 ± 6	0.3
Thalamus	22 ± 5	24 ± 5	0.4	19 ± 5	26 ± 4	0.007*	22 ± 5	24 ± 3	0.4
Cerebellum	42 ± 6	40 ± 16	0.7	31 ± 9	36 ± 8	0.3	42 ± 10	40 ± 14	0.7
Gray matter	50 ± 10	57 ± 15	0.3	37 ± 9	50 ± 9	0.015*	51 ± 7	57 ± 9	0.1

↵* Statistical significance for uncorrected P < 0.05 (unpaired t test between young and old).
Mean ± SD for young (n = 8) and old (n = 7) healthy subjects of percentage increase of K* for ¹¹C-AA, CBF, and V_b after 2S-PVC and 3S-PVC.