TABLE 3

¹²³I-5IA Parameter Estimates For 2-Compartment, 2-Parameter Model Analysis with 6-Hour Scan Time at Different Time Intervals

Volunteer	Frontal cortex					Parietal cortex					Temporal cortex					Occipital cortex					Basal ganglia					Thalamus					Brain stem					Cerebellum
Volunteer		V_T	K₁′	k₂′	V_T	K₁′	k₂′	V_T	K₁′	k₂′	V_T	K₁′	k₂′	V_T	K₁′	k₂′	V_T	K₁′	k₂′	V_T	K₁′	k₂′	V_T	K₁′	k₂′
360 min
Mean	14.6	0.22	0.015	14.2	0.21	0.015	14.6	0.21	0.014	13.2	0.22	0.017	17.6	0.20	0.012	34.3	0.21	0.006	24.7	0.20	0.008	17.8	0.22	0.013
SD	2.5	0.03	0.003	2.3	0.03	0.002	2.4	0.03	0.003	2.6	0.03	0.004	3.7	0.03	0.003	6.9	0.03	0.001	5.7	0.02	0.002	2.0	0.03	0.001
%COV	16.8	15.1	16.8	16.3	12.5	14.8	16.7	16.8	18.8	19.4	15.0	20.6	20.9	13.3	21.2	20.2	12.5	17.4	22.9	12.3	18.7	11.0	14.0	11.8
90 min
Mean	14.8	0.21	0.015	14.1	0.22	0.016	14.1	0.21	0.015	12.6	0.23	0.018	16.2	0.22	0.014	28.4	0.23	0.009	21.8	0.21	0.010	16.1	0.24	0.015
SD	2.1	0.03	0.002	2.5	0.03	0.003	1.9	0.04	0.003	2.1	0.03	0.004	3.8	0.04	0.004	7.2	0.04	0.003	4.8	0.03	0.003	2.1	0.04	0.003
%COV	14.3	15.8	15.5	17.7	14.3	19.9	13.6	18.0	16.9	16.7	15.2	19.6	23.8	17.1	25.1	25.2	17.6	29.8	22.1	15.4	30.0	12.7	16.2	19.1

Values for V_T are given in mL/g, for K₁′ in mL/g/min, and for k₂′ in min⁻¹.