Comparison of T/NT and Target-to-Blood Ratios as Calculated from Biodistribution Data of Different Radioligands in Infected nu/nu Mice 24 h After Injection
| Infection | 123I-ChiB_E144Q | 123I-BSA | 67Ga Citrate |
|---|---|---|---|
| C. albicans | |||
| Muscle | 20.62 ± 3.06 | 2.11 ± 0.57 | 4.83 ± 0.48 |
| Blood | 2.72 ± 0.25 | 0.59 ± 0.11 | 1.57 ± 0.07 |
| A. fumigatus | |||
| Muscle | 15.16 ± 3.72 | 1.44 ± 1.69 | 5.59 ± 2.72 |
| Blood | 1.47 ± 0.22 | 0.60 ± 0.79 | 3.06 ± 1.26 |
| E. coli | |||
| Muscle | 3.03 ± 2.30 | 1.69 ± 0.89 | 3.11 ± 1.28 |
| Blood | 0.57 ± 0.40 | 0.34 ± 0.14 | 1.43 ± 0.49 |
| S. aureus | |||
| Muscle | 4.86 ± 2.62 | ND | ND |
| Blood | 0.62 ± 0.24 | ND | ND |
| Sterile inflam. | |||
| Muscle | 5.31 ± 2.83 | ND | ND |
| Blood | 0.91 ± 0.81 | ND | ND |
ND = not determined; inflam. inflammation.
Data are expressed as %ID/g ± SD (n = 4 mice/group).