TABLE 4

Biodistribution Data of 123I-ChiB_E144Q in Infected nu/nu Mice 24 h After Injection

BiodistributionC. albicansA. fumigatusE. coliS. aureusSterile inflammationA. fumigatus*
Blood0.70 ± 0.020.66 ± 0.050.92 ± 0.590.72 ± 0.130.66 ± 0.050.99 ± 0.31
Muscle0.09 ± 0.010.11 ± 0.080.24 ± 0.160.10 ± 0.020.11 ± 0.080.27 ± 0.10
Abscess1.91 ± 0.132.07 ± 0.010.47 ± 0.310.46 ± 0.260.60 ± 0.060.47 ± 0.19
Lung0.37 ± 0.090.31 ± 0.020.42 ± 0.140.45 ± 0.040.47 ± 0.020.87 ± 0.07
Spleen0.26 ± 0.030.18 ± 0.020.24 ± 0.030.31 ± 0.050.16 ± 0.026.37 ± 1.29
Kidney0.61 ± 0.130.29 ± 0.040.41 ± 0.100.52 ± 0.100.26 ± 0.053.28 ± 1.08
Liver0.35 ± 0.010.22 ± 0.020.23 ± 0.040.38 ± 0.050.16 ± 0.0216.32 ± 3.83
Intestine0.27 ± 0.040.07 ± 0.020.21 ± 0.090.23 ± 0.030.08 ± 0.020.41 ± 0.11
Bladder1.60 ± 0.580.73 ± 0.330.57 ± 0.270.62 ± 0.270.41 ± 0.321.29 ± 0.32
Stomach3.06 ± 1.570.82 ± 0.253.48 ± 2.552.47 ± 0.480.74 ± 0.252.16 ± 1.38
  • * Results of 123I-BSA in A. fumigatus infection.

  • Data are expressed as %ID/g ± SD (n = 4 mice/group).