TABLE 5

Organ Masses, Residence Times (τ), and Dose per Injected Activity for ¹⁷⁷Lu-DOTA-Tyr³-Octreotate in Rats According to Uptake Data of de Jong et al. and Lewis et al.

Organ	de Jong et al.(9)					Lewis et al.(7)
Organ		Mass (g)	τ (min)	Dose (mGy/MBq)	Mass (g)	τ (min)	Dose (mGy/MBq)
Blood	13	14		18	11
Pancreas	0.93	186	260*	1.2	194	216*
Adrenals	0.05	26		0.04	16
Kidneys	2.1	200	130	2.2	133	89
Liver	10	40	5.8	11	26	3.6
Stomach	1.6	57	50*	4.6	40	12*
Thymus	0.46	3.3	8.8	0.44	2.5	6.9
Pituitary	0.02	3.0		0.009	3.4
Femur	1	2.3	6.7	1	49	48
Muscle	118	13	0.39	37	9.2	0.72
Spleen	0.66	2.5	5.6	0.55	1.5	4.1
CA20948†	3	476	212*	1.2	205	225*

↵* For pancreas, adrenals, stomach, pituitary, and tumor, uptakes and dose per injected activity are only valid at used peptide mass of 0.5 μg with 3 MBq ¹⁷⁷Lu (9) or 0.67 μg with 1.3 MBq ¹⁷⁷Lu (7).
↵† CA20948 tumors.