Biodistribution in Tumored Mice 3 Hours After Administration of 99mTc-MORF (Study 3)
| Organ | Amplification | Control I | P value* |
|---|---|---|---|
| [1] | [2] | [1] vs. [2] | |
| Liver | 0.55 ± 0.04 | 0.38 ± 0.11 | 0.064 |
| Heart | 0.19 ± 0.01 | 0.13 ± 0.02 | 0.016 |
| Kidney | 15.2 ± 0.38 | 10.5 ± 2.49 | 0.255 |
| Lung | 0.38 ± 0.02 | 0.31 ± 0.02 | 0.479 |
| Spleen | 0.89 ± 0.16 | 0.88 ± 0.19 | 0.723 |
| Muscle | 0.08 ± 0.00 | 0.14 ± 0.04 | 0.038 |
| Tumor | 0.60 ± 0.08 | 0.18 ± 0.03 | 0.003 |
| Blood | 0.44 ± 0.03 | 0.22 ± 0.03 | 0.001 |
Study animals (amplification targeting) received unlabeled antibody 73 h earlier and unlabeled polymer 43 h earlier (Fig. 1). Control animals did not receive antibody.
↵* Student t test for significance, P < 0.05 (statistically significant values are underlined).
Data are expressed as average %ID/g ± SD; n = 4.