Individual Parameters of 13 Patients Who Had PET Studies of Knees, Wrists, and MCP and PIP Joints
| Patient | Parameters studied | ||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Clinical | Biologic | US | Composite indices | 18F-FDG PET | |||||||||||||||||||||||||||||
| DD (y) | S (n) | T (n) | PGA (mm) | PhyGA (mm) | MS (min) | HAQ | ESR (mm/h)* | CRP (mg/L) | US (n)† | CST (mm) | Doppler‡ | Doppler score§ | DAS28 | SDAI | PET¶ | CSUV | |||||||||||||||||
| 1 | 8 | 14 | 24 | 90 | 88 | 150 | 2.50 | 53 | 81 | 17 | 66.1 | 9 | 21 | 8.1 | 60.9 | 23 | 61.9 | ||||||||||||||||
| 2 | 7 | 13 | 17 | 82 | 79 | 90 | 1.87 | 33 | 5 | 6 | 14.5 | 3 | 5 | 7.2 | 50.5 | 11 | 10.5 | ||||||||||||||||
| 3 | 7 | 20 | 15 | 87 | 84 | 180 | 1.25 | 26 | 22 | 18 | 63.1 | 9 | 23 | 7.2 | 58.3 | 19 | 31.1 | ||||||||||||||||
| 4 | 3 | 10 | 11 | 63 | 49 | 120 | 1.62 | 14 | 23 | 3 | 9.9 | 0 | 0 | 5.6 | 36.5 | 4 | 8.3 | ||||||||||||||||
| 5 | 7 | 24 | 24 | 96 | 94 | 300 | 2.50 | 40 | 35 | 18 | 44.6 | 5 | 15 | 8.3 | 75.5 | 20 | 27.3 | ||||||||||||||||
| 6 | 10 | 24 | 24 | 58 | 93 | 15 | 2.12 | 69 | 29 | 15 | 42.6 | 0 | 0 | 8.2 | 73.0 | 20 | 24.6 | ||||||||||||||||
| 7 | 18 | 22 | 22 | 88 | 87 | 240 | 1.25 | 31 | 60 | 22 | 46.8 | 8 | 16 | 7.8 | 71.5 | 24 | 42.3 | ||||||||||||||||
| 8 | 18 | 20 | 21 | 93 | 91 | 240 | 2.25 | 84 | 41 | 14 | 41.0 | 0 | 0 | 8.5 | 69.5 | 19 | 23.4 | ||||||||||||||||
| 9 | 9 | 17 | 17 | 92 | 94 | 300 | 2.75 | 46 | 97 | 17 | 51.3 | 2 | 5 | 7.7 | 67.3 | 15 | 23.0 | ||||||||||||||||
| 10 | 1 | 12 | 8 | 58 | 70 | 60 | 1.62 | 12 | 11 | 7 | 10.5 | 0 | 0 | 5.2 | 34.9 | 0 | 6.0 | ||||||||||||||||
| 11 | 14 | 16 | 20 | 94 | 94 | 90 | 2.25 | 14 | 36 | 9 | 30.3 | 3 | 10 | 6.9 | 62.4 | 14 | 26.1 | ||||||||||||||||
| 12 | 1 | 21 | 21 | 65 | 87 | 120 | 1.62 | 36 | 55 | 4 | 20.0 | 0 | 0 | 7.5 | 67.7 | 13 | 26.8 | ||||||||||||||||
| 13 | 16 | 17 | 17 | 88 | 84 | 150 | 2.00 | 54 | 70 | 18 | 61.3 | 1 | 2 | 7.6 | 59.2 | 16 | 26.9 | ||||||||||||||||
↵* Millimeters per first hour.
↵† No. of joints with synovial thickness ≥1 mm measured by US.
↵‡ No. of joints with at least 1 power Doppler signal.
↵§ Sum of all scores attributed to all detected signals.
↵¶ No. of joints where synovitis is observed on 18F-FDG PET analysis.
DD = disease duration; S = swollen joints; T = tender joints; MS = morning stiffness.
The clinical parameters swelling and tenderness, sonographic, and PET parameters were determined on the same 24 joints (knees, wrists, and MCP and PIP joints), whereas indices DAS28 and SDAI were calculated using a 28-joint count (the same 24, plus elbows and shoulders).