Clearance, Protein Binding, Red Cell Binding, and Urine Excretion of 99mTc-MAEC Complexes in Humans Compared with Simultaneously Injected 131I-OIH (n = 3)
| 99mTc-MAEC | 99mTc-MAEC clearance (mL/min) | 131I-OIH clearance (mL/min) | 99mTc-MAEC/131I-OIH clearance ratio (%) | Protein binding (%) | Red cell binding (%) | 99mTc-MAEC/131I-OIH 30-min urine ratio (%) | 99mTc-MAEC/131I-OIH 180-min urine ratio (%) |
|---|---|---|---|---|---|---|---|
| syn-l | 305 ± 35 | 621 ± 20 | 49 ± 4 | 89.3 ± 0.6 | 20.3 ± 5.5 | 86 ± 2 | 98 ± 6 |
| anti-l | 254 ± 71 | 556 ± 133 | 45 ± 4 | 87.7 ± 1.5 | 19.0 ± 6.1 | 73 ± 12 | 97 ± 6 |
| syn-d | 431 ± 84 | 591 ± 150 | 74 ± 6 | 86.5 ± 2.1 | 20.3 ± 2.1 | 96 ± 2 | 104 ± 1 |
| anti-d | 277 ± 92 | 472 ± 87 | 59 ± 20 | 82.0 ± 5.2 | 22.7 ± 5.0 | 79 ± 16 | 100 ± 2 |
Data are presented as mean ± SD.