Biodistribution and T/NT Tissue Ratios in M109 Tumor-Bearing BALB/c Mice Fed Leucovorin-Supplemented Folate-Deficient Diets
| Organ | Folate-deficient diet + leucovorin | ||
|---|---|---|---|
| %ID/g | T/NT | ||
| Blood | 0.26 ± 0.07 | 67.67 ± 7.40 | |
| Heart | 2.20 ± 0.06 | 7.83 ± 1.75 | |
| Lung | 1.58 ± 0.19 | 10.79 ± 1.46 | |
| Liver | 4.22 ± 0.04 | 4.08 ± 1.00 | |
| Intestine | 3.04 ± 2.04 | 7.12 ± 3.96 | |
| Kidney | 109.90 ± 12.78 | 0.16 ± 0.04 | |
| Muscle | 1.99 ± 0.39 | 8.64 ± 1.11 | |
| Spleen | 0.44 ± 0.07 | 38.72 ± 3.98 | |
| Tumor | 17.24 ± 4.22 | — | |
| Stomach | 1.43 ± 0.07 | 12.08 ± 2.95 | |
Values are means ± SD (n = 3). BALB/c mice weighed 20 ± 2 g.