Parameter | Mean ± SD for: | Difference (P) for remote vs. normal | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
ROIs in patients with TBI | Healthy volunteers (normal cortex) | |||||||||||
Contusion | PC4.5 | PC13.5 | PC22.5 | Remote | ||||||||
K1 (mL/min) | 0.027 ± 0.021 | 0.064 ± 0.025 | 0.073 ± 0.025 | 0.078 ± 0.027 | 0.095 ± 0.031 | 0.103 ± 0.014 | NS | |||||
k2 (/min) | 0.113 ± 0.075 | 0.192 ± 0.109 | 0.182 ± 0.063 | 0.183 ± 0.089 | 0.198 ± 0.059 | 0.227 ± 0.075 | NS | |||||
k3 (/min) | 0.039 ± 0.018 | 0.069 ± 0.05 | 0.065 ± 0.034 | 0.060 ± 0.035 | 0.061 ± 0.018 | 0.175 ± 0.041 | <0.0001 | |||||
k4 (/min) | 0.015 ± 0.022 | 0.008 ± 0.008 | 0.009 ± 0.008 | 0.009 ± 0.009 | 0.012 ± 0.004 | 0.008 ± 0.004 | <0.01 | |||||
Blood volume (mL/g) | 0.024 ± 0.016 | 0.030 ± 0.043 | 0.035 ± 0.034 | 0.044 ± 0.054 | 0.042 ± 0.032 | 0.041 ± 0.017 | NS | |||||
Ki (mL/min) | 0.006 ± 0.004 | 0.017 ± 0.008 | 0.019 ± 0.009 | 0.019 ± 0.009 | 0.023 ± 0.009 | 0.045 ± 0.007 | <0.0001 | |||||
CBF (mL/g/min) | 0.11 ± 0.08 | 0.31 ± 0.12 | 0.35 ± 0.11 | 0.38 ± 0.12 | 0.46 ± 0.13 | 0.49 ± 0.08 | NS |
NS = not significant.