TABLE 2

Comparison of MBF, MFR, and CVR at Rest and During Pharmacologic Vasodilation in Baseline Evaluation and Caffeine Studies

Subject no.MBF (mL/min/g)MFRCVR (mm Hg/[mL/min/g])
BaselineCaffeineBaselineCaffeineBaselineCaffeine
RestATPDIPRestATPDIPATPDIPATPDIPRestATPDIPRestATPDIP
10.744.263.140.541.551.065.764.242.871.96117.120.327.8144.452.973.6
20.563.451.880.531.171.676.163.362.193.14103.015.927.7114.153.236.7
30.693.184.370.521.542.224.586.292.964.27106.023.817.2144.245.935.0
40.654.142.130.651.631.626.353.272.502.48119.614.937.9119.143.650.8
51.213.733.121.211.711.383.102.591.421.1461.722.626.362.251.761.0
60.632.792.680.512.231.294.464.284.382.52119.827.430.6143.934.465.3
70.653.554.210.651.081.415.466.481.662.17115.919.417.3148.787.058.2
80.654.502.870.861.871.086.924.422.171.26125.614.928.194.237.880.9
91.432.792.801.402.082.141.951.961.491.5354.525.229.456.035.438.2
100.684.632.840.681.911.356.814.182.811.9979.912.019.082.431.445.7
Mean0.793.703.000.751.681.525.154.102.442.25100.319.626.1110.947.354.5
± SD± 0.29± 0.67*± 0.79*± 0.31± 0.37± 0.40± 1.64± 1.44± 0.88± 0.94± 25.7± 5.1*± 6.6*± 35.5± 16.1± 15.9
  • * P < 0.0001 vs. rest in baseline.

  • P < 0.005 vs. ATP in baseline.

  • P < 0.005 vs. rest in baseline.

  • § P < 0.005 vs. DIP in baseline.

  • P < 0.0001 vs. rest in caffeine.

  • DIP = dipyridamole.