TABLE 2

Comparison Between Direct Tissue Counting and Activity Obtained from PET Images

Rat no.Body weight (g)Injected dose (MBq [mCi])Recovery rate*
Whole brainCXTHCBBS
122437.0 [1.000]0.931.020.870.95
223142.7 [1.153]1.231.040.801.36
321837.2 [1.006]0.820.970.880.98
426461.2 [1.655]1.040.801.010.880.52
522655.5 [1.501]1.180.680.950.801.04
623540.3 [1.090]0.720.720.950.841.10
726054.0 [1.460]1.171.180.940.890.86
824157.8 [1.563]1.000.961.000.941.22
926862.9 [1.700]0.940.831.020.791.02
Mean ± SD241 ± 1849.9 ± 10.5[1.348 ± 0.284]1.01 ± 0.170.90 ± 0.190.99 ± 0.040.84 ± 0.051.01 ± 0.24
Correlation coefficient between direct tissue counting and activity obtained from PET images0.710.730.990.960.43
  • * Recovery rate was determined as (activity in MBq/mL in PET image acquired 55–60 min after injection of 18F-FDG)/(activity in dissected tissue in MBq/mL).