TABLE 2

Blood Flows (mL/min/g) and End 99mTc Activities

DogBaseline flowOcclusion flowReperfusion flowEnd flowEnd activity (%ID/[g × 10−3])End activity ratioOcclusion flow ratio
LADLCxLADLCxLADLCxLADLCxLADLCxLCx/LADLCx/LAD
11.25 ± 0.031.05 ± 0.031.29 ± 0.030.41 ± 0.071.44 ± 0.041.03 ± 0.040.94 ± 0.030.45 ± 0.033.4 ± 0.115.2 ± 1.84.50.32
21.64 ± 0.041.47 ± 0.051.03 ± 0.030.27 ± 0.041.11 ± 0.031.27 ± 0.080.82 ± 0.020.70 ± 0.043.0 ± 0.420.1 ± 2.86.60.26
31.17 ± 0.041.19 ± 0.040.95 ± 0.030.63 ± 0.080.67 ± 0.020.80 ± 0.040.63 ± 0.010.54 ± 0.031.3 ± 0.13.7 ± 0.52.80.67
40.70 ± 0.020.72 ± 0.030.77 ± 0.020.44 ± 0.040.83 ± 0.020.72 ± 0.030.67 ± 0.020.52 ± 0.031.0 ± 0.14.8 ± 1.04.80.57
51.09 ± 0.030.89 ± 0.020.78 ± 0.020.21 ± 0.040.82 ± 0.020.86 ± 0.060.66 ± 0.010.43 ± 0.023.3 ± 0.28.3 ± 1.22.50.27
61.45 ± 0.061.55 ± 0.051.23 ± 0.030.38 ± 0.071.96 ± 0.051.78 ± 0.091.09 ± 0.030.88 ± 0.033.0 ± 0.315.5 ± 2.35.20.31
All dogs1.22 ± 0.131.15 ± 0.131.01 ± 0.090.39 ± 0.06*1.14 ± 0.201.08 ± 0.160.80 ± 0.080.60 ± 0.072.5 ± 0.411.3 ± 2.74.4 ± 0.60.40 ± 0.07
  • * P ≤ 0.001 compared with LAD.

  • End activity is expressed as percentage of injected dose per gram of tissue × 10−3.