TABLE 1

Computed Rate Constants Describing 18F-FHBG Kinetics (Based on Model in Figure 2)

RatsK1k2k3Ki
mHSV1-tk (n = 7)0.069 ± 0.0260.222 ± 0.139*0.084 ± 0.031*0.199 ± 0.008*
Control (null vector) (n = 2)0.123†0.508 ± 0.7410.005 ± 0.0010.001 ± 0.000

  • ↵* P < 0.05 compared with data from null vector rats.

  • ↵† n = 1 only; estimate of K1 in 1 rat was unreliable.