TABLE 1

Fetal Dose in Early Pregnancy and at End of Each Trimester of Pregnancy

Radiopharmaceutical: 18F-FDGEarly pregnancy (mGy/MBq)Gestation
3 mo (mGy/MBq)6 mo (mGy/MBq)9 mo (mGy/MBq)
Russell et al. (1)2.7 × 10−21.7 × 10−29.4 × 10−38.1 × 10−3
MIRD DER (no crossover, 2-h void)1.8 × 10−29.6 × 10−36.5 × 10−35.5 × 10−3
MIRD DER (no crossover, 4-h void)2.2 × 10−21.3 × 10−27.9 × 10−36.8 × 10−3
MIRD DER (crossover, 2-h void)1.8 × 10−21.8 × 10−21.6 × 10−21.5 × 10−2
MIRD DER (crossover, 4-h void)2.2 × 10−22.2 × 10−21.7 × 10−21.7 × 10−2
  • Values suggested by Russell et al. (1) are compared with new values including placental transfer of activity (3) and updated maternal organ activity values (4).