Calculated Mean Absorbed Dose in Tumors at Maximum Tolerated Dose (MTD)
| Radioimmunoconjugate preparation | Self-dose S value* (mGy/MBq · s) | AUC (h) | Absorbed tumor dose (Gy) |
|---|---|---|---|
| 131I-cG250 | 1.305 | 29.16 | 76 |
| 186Re-MAG3-cG250 | 1.9215 | 16.30 | 104 |
| 90Y-SCN-Bz-DTPA-cG250 | 2.055 | 46.17 | 95 |
| 177Lu-SCN-Bz-DTPA-cG250 | 1.2035 | 201.44 | 807 |
↵* For tumors of 0.055 g (MIRDOSE3, unit density sphere model) (24).
AUC = area under the curve.