Characteristics of Radiolabeled Immunoconjugates
| Preparation | Maximum specific activity in kBq/μg (μCi/μg) | Labeling efficiency (%) | RCP after purification (%) | Immunoreactivity (%) |
|---|---|---|---|---|
| 90Y-cDTPA-cG250 | 370 (10) | 13 | 86 | ND |
| 90Y-SCN-Bz-DTPA-cG250 | 370 (10) | 90 | 98 | 100 |
| 90Y-DOTA-cG250 | 111 (3) | 94 | 98 | 80 |
| 177Lu-cDTPA-cG250 | 296 (8) | 15 | 75 | 89 |
| 177Lu-SCN-Bz-DTPA-cG250 | 296 (8) | 97 | 98 | 82 |
| 177Lu-DOTA-cG250 | 111 (3) | 94 | 99 | 87 |
| 131I-cG250 | 1,850 (50) | 87 | 98 | 96 |
| 186Re-MAG3-cG250 | 307 (8) | 43 | 99 | 95 |
RCP = radiochemical purity; ND = not determined.