TABLE 1

Indications for CT Contrast Agents in Combined PET/CT

PET/CT indicationFull-dose CT with intravenous and oral contrast*Low-dose CT without contrast
Staging and restaging
 Tumor stagingRINA
 Tumor restagingRINA
Therapy planning
 RT planning: head and neck, abdomen, pelvisRINA
 RT planning: thoraxRTIR
 Surgical planningRINA
 Interventional planning: separate contrast-enhanced CT availableINAR
 Interventional planning: no contrast-enhanced CT availableRINA
Therapy control
 Chemotherapy/irradiation)INAR
 Surgical/interventional)INAR
  • R = recommended; RT = radiation therapy; RTI = recommended if tumor invasion into mediastinum is suspected; INA = for indication not appropriate.

  • * Oral contrast applicable when abdomen in the field of view.