Biodistribution of 67Ga-IMP 241 Given 24 Hours After 125I-hMN-14 × 679-F(ab′)2 bsAb
| Ratio | Time after injection of peptide (+ 24 h after injection of bsAb) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 1 h | 2 h | 3 h | 4 h | 6 h | |||||
| Liver | 8.0 ± 3.8 | 15.9 ± 8.9 | 13.1 ± 12.0 | 16.2 ± 8.6 | 16.0 ± 10.5 | ||||
| Spleen | 10.7 ± 7.2 | 26.6 ± 28.7 | 16.3 ± 13.1 | 26.1 ± 23.4 | 17.4 ± 12.7 | ||||
| Kidney | 2.3 ± 1.6 | 3.5 ± 2.2 | 2.4 ± 1.8 | 3.1 ± 1.1 | 4.3 ± 2.7 | ||||
| Lungs | 4.5 ± 1.9 | 13.1 ± 7.5 | 11.4 ± 11.1 | 13.5 ± 5.9 | 20.2 ± 12.5 | ||||
| Blood | 1.7 ± 0.8 | 6.1 ± 5.0 | 8.5 ± 9.5 | 8.7 ± 4.6 | 12.1 ± 8.0 | ||||
| Stomach | 36.7 ± 22.8 | 52.8 ± 17.6 | 73.6 ± 47.4 | 56.9 ± 36.0 | 112.5 ± 60.7 | ||||
| Small intestine | 18.6 ± 9.1 | 27.7 ± 9.1 | 35.5 ± 26.0 | 22.0 ± 12.7 | 47.2 ± 35.9 | ||||
| Large intestine | 67.3 ± 44.1 | 74.2 ± 55.0 | 72.7 ± 89.0 | 56.5 ± 21.7 | 162.3 ± 270 | ||||
| Bone | 11.5 ± 11.0 | 24.6 ± 15.1 | 17.8 ± 13.7 | 18.3 ± 3.1 | 53.0 ± 41.7 | ||||
Data are expressed as tumor-to-tissue ratios ± SD (5 animals per group).