Biodistribution of 67Ga-IMP 241 Given Alone, with No bsAb Pretargeting
| Tissue | Time after injection of 67Ga-IMP 241 peptide | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 1 h | 2 h | 3 h | 4 h | 6 h | |||||
| Tumor | 0.7 ± 0.4 | 0.3 ± 0.1 | 0.2 ± 0.1 | 0.2 ± 0.0 | 0.1 ± 0.0 | ||||
| Liver | 0.1 ± 0.0 | 0.1 ± 0.0 | 0.1 ± 0.0 | 0.1 ± 0.0 | 0.1 ± 0.0 | ||||
| Spleen | 0.0 ± 0.0 | 0.1 ± 0.1 | 0.1 ± 0.0 | 0.1 ± 0.0 | 0.1 ± 0.0 | ||||
| Kidney | 2.2 ± 0.8 | 1.7 ± 0.5 | 2.6 ± 0.7 | 2.0 ± 0.4 | 2.6 ± 0.5 | ||||
| Lungs | 0.1 ± 0.1 | 0.1 ± 0.1 | 0.1 ± 0.0 | 0.0 ± 0.0 | 0.1 ± 0.0 | ||||
| Blood | 0.1 ± 0.0 | 0.1 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 | ||||
| Stomach | 0.1 ± 0.1 | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.1 ± 0.1 | 0.0 ± 0.0 | ||||
| Small intestine | 0.3 ± 0.3 | 0.1 ± 0.1 | 0.1 ± 0.1 | 0.3 ± 0.2 | 0.0 ± 0.0 | ||||
| Large intestine | 0.1 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.5 ± 0.8 | 0.1 ± 0.0 | ||||
| Bone | 0.1 ± 0.1 | 0.1 ± 0.0 | 0.1 ± 0.0 | 0.1 ± 0.0 | 0.0 ± 0.0 | ||||
Data are expressed as percentage injected dose per gram (%ID/g) of tissue ± SD (5 animals per group).