Biodistribution of 125I-hMN-14 × 679-F(ab′)2 bsAb Given 24 Hours Before 67Ga-Labeled Peptide
| Tissue | Time after injection of peptide (+ 24 h after injection of bsAb) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 1 h | 2 h | 3 h | 4 h | 6 h | |||||
| Tumor | 3.1 ± 1.0 | 2.4 ± 0.9 | 1.5 ± 0.6 | 2.5 ± 0.9 | 2.5 ± 1.2 | ||||
| Liver | 0.7 ± 0.1 | 0.4 ± 0.1 | 0.5 ± 0.2 | 0.4 ± 0.1 | 0.5 ± 0.1 | ||||
| Spleen | 1.0 ± 0.4 | 0.6 ± 0.4 | 0.6 ± 0.1 | 0.6 ± 0.3 | 0.7 ± 0.3 | ||||
| Kidney | 0.7 ± 0.1 | 0.5 ± 0.1 | 0.5 ± 0.1 | 0.4 ± 0.1 | 0.4 ± 0.1 | ||||
| Lungs | 0.8 ± 0.3 | 0.4 ± 0.1 | 0.4 ± 0.1 | 0.4 ± 0.1 | 0.5 ± 0.1 | ||||
| Blood | 1.5 ± 0.2 | 1.0 ± 0.3 | 0.8 ± 0.2 | 0.9 ± 0.2 | 1.0 ± 0.3 | ||||
| Stomach | 2.9 ± 0.7 | 1.3 ± 1.0 | 1.6 ± 1.2 | 1.5 ± 1.1 | 2.4 ± 1.8 | ||||
| Small intestine | 0.3 ± 0.1 | 0.2 ± 0.1 | 0.2 ± 0.1 | 0.2 ± 0.1 | 0.2 ± 0.1 | ||||
| Large intestine | 0.3 ± 0.0 | 0.3 ± 0.1 | 0.3 ± 0.1 | 0.3 ± 0.1 | 0.3 ± 0.2 | ||||
| Bone | 0.5 ± 0.1 | 0.2 ± 0.1 | 0.3 ± 0.1 | 0.2 ± 0.1 | 0.2 ± 0.1 | ||||
Data are expressed as percentage injected dose per gram (%ID/g) of tissue ± SD (5 animals per group).