TABLE 1

Radiation Dosimetry of 18F-FDHT in Prostate Cancer Patients

Target organAbsorbed dose (cGy/MBq)% SD
Patient 1Patient 2Patient 3Patient 4Patient 5Patient 6Patient 7MeanSD
Study 1 248 MBgStudy 1 407 MBgStudy 2 189 MBgStudy 1 111 MBgStudy 2 281 MBgStudy 1 407 MBgStudy 2 407 MBgStudy 1 270 MBgStudy 1 396 MBgStudy 1 377 MBg
Adrenals0.001510.001260.000870.001560.000770.000850.001130.000990.000570.001320.001080.00032930
Brain0.001080.000660.000230.001070.000450.000500.000780.000420.000060.000860.000610.00034156
Gallbladder wall0.001650.001540.001310.001720.000920.000960.001230.001290.000740.001420.001280.00032626
Lower large intestine wall0.001430.001080.000780.001430.000960.001060.001340.000880.000410.001320.001070.00032731
Small intestine0.001480.001060.000630.001490.000790.000860.001190.000790.000320.001270.000990.00037938
Stomach0.001390.000950.000480.001390.000630.000690.001020.000700.000300.001180.000870.00037543
Upper large intestine wall0.001460.001070.000650.001480.000760.000830.001150.000800.000330.001250.000980.00036938
Heart wall0.001390.000990.000550.001410.000640.000690.001020.000720.000270.001150.000880.00037442
Kidneys0.001410.001090.000680.001430.000690.000760.001050.000840.000460.001230.000960.00032834
Liver0.002570.004570.005970.003030.002270.002180.001890.004650.003680.002490.003330.00134440
Lungs0.001250.000890.000490.001260.000570.000620.000910.000650.000250.001040.000790.00033242
Muscle0.001200.000820.000450.001200.000600.000660.000940.000600.000200.001010.000770.00032442
Pancreas0.001550.001210.000760.001570.000760.000820.001150.000970.000590.001390.001080.00035032
Red marrow0.001820.002310.001670.002210.001350.001840.001720.001710.001930.002160.001870.00029316
Bone surfaces0.001630.001660.001060.001840.001000.001310.001400.001190.001110.001690.001390.00030022
Skin0.000950.000610.000280.000950.000430.000470.000710.000420.000100.000780.000570.00028149
Spleen0.001790.001720.000380.001330.001160.001170.001400.003110.006730.004540.002330.00194183
Testes0.001170.000800.000510.001150.000710.000760.001030.000620.000200.001020.000790.00030739
Thymus0.001250.000800.000330.001250.000530.000580.000910.000530.000120.001010.000730.00037852
Thyroid0.001230.000750.000270.001230.000510.000560.000890.000480.000070.000980.000700.00039156
Urinary bladder wall0.001510.006590.015030.001060.012780.013380.011050.010380.008810.006160.008680.00480855
Total body0.001250.000960.000630.001270.000670.000740.000990.000740.000360.001090.000870.00029234
Effective dose equivalent (cSv/MBq)0.001520.001780.002010.001590.001700.001840.001880.001860.001650.001890.001770.0001529