TABLE 1

18F-FDG PET vs. WBC/Marrow Imaging in 59 Joint Replacements

ParameterSensitivitySpecificityAccuracyPPVNPV
PPA1.00 (25/25)0.09 (3/34)0.47 (28/59)0.45 (25/56)1.00 (3/3)
FDG/Ma0.96 (24/25)0.35 (12/34)0.61 (36/59)0.52 (24/46)0.92 (12/13)
BPI0.52 (13/25)0.44 (15/34)0.47 (28/59)0.40 (13/32)0.56 (15/27)
T/B ratio0.36 (9/25)0.97 (33/34)0.71 (42/59)0.90 (9/10)0.67 (33/49)
WBC/Ma1.00 (25/25)0.91 (31/34)0.95 (56/59)0.89 (25/28)1.00 (31/31)
  • PPV = positive predictive value; NPV = negative predictive value; PPA = any periprosthetic activity; FDG/Ma = FDG/marrow; BPI = BPI activity; T/B ratio = target-to-background ratio; WBC/Ma = labeled leukocyte/marrow.