TABLE 1

Biodistribution of ¹⁸F-FDG and ¹⁴C-2DG in Nude Mice Bearing LS174T Human Tumor Xenografts

Tissue %ID/g*	¹⁸F-FDG					¹⁴C-2DG		P (n = 12)
Tissue %ID/g*		0.5 h	1 h	2 h	0.5 h	1 h	2 h	P (n = 12)
Blood	0.71 ± 0.08	0.35 ± 0.19	0.21 ± 0.05	0.98 ± 0.53	1.18 ± 0.55	1.17 ± 0.13	0.013
Liver	0.96 ± 0.14	0.62 ± 0.24	0.60 ± 0.21	1.57 ± 0.78	1.23 ± 0.32	1.27 ± 0.38	0.016
Kidney	2.25 ± 0.52	1.40 ± 0.63	1.44 ± 0.31	2.67 ± 1.09	2.60 ± 1.17	2.93 ± 0.49	0.024
Lung	2.56 ± 1.00	2.11 ± 0.85	2.65 ± 0.80	1.62 ± 0.18	2.41 ± 1.33	2.77 ± 0.62	0.672
Spleen	2.15 ± 0.47	2.11 ± 0.57	2.52 ± 0.23	2.46 ± 0.76	2.24 ± 1.73	4.11 ± 1.26	0.418
Colon	4.32 ± 0.70	4.36 ± 1.82	3.39 ± 0.63	3.61 ± 0.38	4.18 ± 1.39	5.15 ± 0.59	0.625
Muscle	2.32 ± 0.83	2.69 ± 0.17	3.75 ± 1.50	2.04 ± 0.76	3.29 ± 1.01	4.97 ± 0.86	0.525
Brain	5.57 ± 0.70	3.83 ± 1.46	3.12 ± 0.57	3.81 ± 1.29	3.51 ± 0.89	4.05 ± 1.23	0.633
Heart	9.19 ± 1.66	10.16 ± 2.31	8.81 ± 1.68	6.96 ± 2.61	9.43 ± 3.37	7.75 ± 1.51	0.158
Tumor	3.34 ± 0.96	2.77 ± 1.89	2.62 ± 1.38	2.92 ± 1.13	4.46 ± 2.92	3.15 ± 0.73	0.304