Site | TP | TN | FP | FN | Sensitivity (%) [95% CI] | Specificity (%) [95% CI] | PPV (%) [95% CI] | NPV (%) [95% CI] | Accuracy (%) [95% CI] | |
---|---|---|---|---|---|---|---|---|---|---|
Peritoneum | PET | 7 | 45 | 2 | 1 | 87.5 [47.3–99.7] | 95.7 [85.5–99.5] | 77.8 [40.0–97.2] | 97.8 [88.5–99.9] | 94.5 [84.9–98.9] |
CT/MRI | 0 | 47 | 0 | 8 | 0 [—] | 100 [—] | N/A | 85.5 [73.3–93.5] | 85.5 [73.3–93.5] | |
Bone | PET | 0 | 54 | 1 | 0 | N/A | 98.2 [90.3–100] | 0 [—] | 100 [—] | 98.2 [90.3–100] |
CT/MRI | 0 | 52 | 3 | 0 | N/A | 94.5 [84.9–98.9] | 0 [—] | 100 [—] | 94.5 [84.9–98.9] | |
Liver/spleen | PET | 2 | 52 | 1 | 0 | 100 [—] | 98.1 [89.9–100] | 66.7 [9.4–99.2] | 100 [—] | 98.2 [90.3–100] |
CT/MRI | 0 | 52 | 1 | 2 | 0 [—] | 98.1 [89.9–100] | 0 [—] | 96.3 [87.3–99.5] | 94.5 [84.9–98.9] | |
Lung | PET | 7 | 46 | 0 | 2 | 77.8 [40.0–97.2] | 100 [—] | 100 [—] | 95.8 [85.7–99.5] | 96.4 [87.5–99.6] |
CT/MRI | 4 | 46 | 0 | 5 | 44.4 [13.7–78.8] | 100 [—] | 100 [—] | 90.2 [78.6–96.7] | 90.9 [80.0–97.0] | |
Mediastinum | PET | 10 | 44 | 1 | 0 | 100 [—] | 97.8 [88.2–99.9] | 90.9 [58.7–99.8] | 100 [—] | 98.2 [90.3–100] |
CT/MRI | 2 | 43 | 2 | 8 | 20.0 [2.5–55.6] | 95.6 [84.9–99.5] | 50.0 [6.8–93.2] | 84.3 [71.4–93.0] | 81.8 [69.1–90.9] | |
Supraclavicular LN | PET | 11 | 41 | 1 | 2 | 84.6 [54.6–98.1] | 97.6 [87.4–99.9] | 91.7 [61.5–99.8] | 95.3 [84.2–99.4] | 94.5 [84.9–98.9] |
CT/MRI | 9 | 42 | 0 | 4 | 69.2 [38.6–90.9] | 100 [—] | 100 [—] | 91.3 [79.2–97.6] | 92.7 [82.4–98.0] | |
Paraaortic LN | PET | 15 | 38 | 0 | 2 | 88.2 [63.6–98.5] | 100 [—] | 100 [—] | 95.0 [83.1–99.4] | 96.4 [87.5–99.6] |
CT/MRI | 9 | 37 | 1 | 8 | 52.9 [27.8–77.0] | 97.4 [86.2–99.9] | 90.0 [55.5–99.7] | 82.2 [67.9–92.0] | 83.6 [71.2–92.2] | |
Pelvic LN | PET | 10 | 43 | 1 | 1 | 90.9 [58.7–99.8] | 97.7 [88.0–99.9] | 90.9 [58.7–99.8] | 97.7 [88.0–99.9] | 96.4 [87.5–99.6] |
CT/MRI | 3 | 44 | 0 | 8 | 27.3 [6.0–61.0] | 100 [—] | 100 [—] | 84.6 [71.9–93.1] | 85.5 [73.3–93.5] | |
Inguinal LN | PET | 4 | 51 | 0 | 0 | 100 [—] | 100 [—] | 100 [—] | 100 [—] | 100 [—] |
CT/MRI | 2 | 51 | 0 | 2 | 50.0 [6.8–93.2] | 100 [—] | 100 [—] | 96.2 [87.0–1.0] | 96.4 [87.5–99.6] | |
Metastatic lesions | PET | 66 | 414 | 7 | 8 | 89.2 [79.8–95.2] | 98.3 [96.6–99.3] | 90.4 [81.2–96.1] | 98.1 [96.3–99.2] | 97.0 [95.1–98.3] |
CT/MRI | 29 | 414 | 7 | 45 | 39.2 [28.0–51.2] | 98.3 [96.6–99.3] | 80.6 [64.0–91.8] | 90.2 [87.1–92.8] | 89.5 [86.5–92.1] | |
Central or pelvic recurrent or persistent tumors | PET | 18 | 34 | 1 | 2 | 90.0 [68.3–98.8] | 97.1 [85.1–99.9] | 94.7 [74.0–99.9] | 94.4 [81.3–99.3] | 94.5 [84.9–98.9] |
CT/MRI | 16 | 34 | 1 | 4 | 80.0 [56.3–94.3] | 97.1 [85.1–99.9] | 94.1 [71.3–99.9] | 89.5 [75.2–97.1] | 90.9 [80.0–97.0] | |
Total lesions | PET | 84 | 448 | 8 | 10 | 89.4 [81.3–94.8] | 98.2 [96.6–99.2] | 91.3 [83.6–96.2] | 97.8 [96.0–98.9] | 96.7 [94.9–98.0] |
CT/MRI | 45 | 448 | 8 | 49 | 47.9 [37.5–58.4] | 98.2 [96.6–99.2] | 84.9 [72.4–93.3] | 90.1 [87.2–92.6] | 89.6 [86.8–92.1] |
PPV = positive predictive value; NPV = negative predictive value; N/A = not applicable.