TABLE 1

Patient Characteristics and Detectability of Hypermetabolic Lesions on ¹⁸F-FLT PET as Compared with Standard ¹⁸F-FDG PET

Patient no.	Age (y)	Sex	Histology	TNM	Stage	Previous therapy	Interval between treatment and PET	Consensus ¹⁸F-FDG result							Consensus ¹⁸F-FLT result
Patient no.	Age (y)	Sex	Histology	TNM	Stage	Previous therapy	Interval between treatment and PET									TL	N1	N2	D	TL	N1	N2	D
Patients with pretreatment
1	57	F	AC	T2 N2-3 M1	IV	Cisplatin and gemcitabine	27 mo	4	1	4	2	1	1	2	2*
2	56	F	AC	T2 N3 M1	IV	Docetaxel	14 mo	1	0	1	3*	2	0	0	3*
3	64	F	AC	T4 N0 M1	IV	Cisplatin and gemcitabine and second-line paclitaxel and docetaxel	Just before third cycle of docetaxel	2	0	0	1	1	0	0	0
4	58	M	SCC	T4 N1 M1	IV	Epirubicin and gemcitabine	9 mo	1	1	0	1	1	0	0	0
5	62	M	LCUC	T4 N2 M0	IIIB	Cisplatin and gemcitabine	17 mo	1	0	0	0	1	0	0	0
6	54	F	AC	T4 N2 M1	IV	Cisplatin and gemcitabine and second-line docetaxel and irinotecan	1 mo	4	0	1	11*	2	0	1	2
7	45	M	SCC	T1 N0 M1	IV	Radiotherapy on abdomen (in 1983), mediastinum (in 1983), and head and neck and supraclavicular region (in 2000)	20 mo	0	0	0	2	0	0	0	1
8	61	M	SCC	T2 N2 M1	IV	Radiotherapy on recurrent tumor	2 mo	1	0	1	1*	0	0	0	1
9	53	M	AC	Tx N2/3 M1	IV	Radiotherapy on acetabulum	1 wk	5	0	1	30*	0	0	0	0
Patients without pretreatment
10	57	M	SCC	T2 N0 M0	IB	None	NA	1	0	0	0	1	0	0	0
11	70	M	SCC	T2 N2 M0	IIIA	None	NA	1	0	1	0	0	1	1	0
12	67	M	SCC	T4 N0 M1	IV	None	NA	1	0	0	1*	1	0	0	1*
13	73	M	SCC	T4 N2 M0	IIIB	None	NA	1	0	0	0	1	0	0	1
14	74	M	SCC	T4 N2 M0	IIIB	None	NA	0	0	3	0	0	0	3	1
15	65	M	LCUC	T4 N2 M1	IV	None	NA	1	1	1	1*	1	0	0	0
16	43	F	AC	T4 N2 M1	IV	None	NA	2	0	3	2	1	1	2	0
17	52	M	NM	NM		None	NA	0	0	0	0	0	0	0	0
							Total	26	3	16	55	13	3	9	12

↵* Including pulmonary lesions located outside the lobe containing the primary tumor.
TL = lesions in lungs; N1 = lesions located at N1 node; N2 = lesions located at N2; D = distant hypermetabolic lesions; AC = adenocarcinoma; SCC = squamous cell carcinoma; LCUC = large cell undifferentiated carcinoma; NA = not applicable; NM = no malignancy.