Cumulated Activity and Residence Time of 18F-FLT for 37-MBq Injection and Standard Man
| Source organ | n | C̃ (kBq-h/g) | SD C̃ (kBq-h/g) | Organ wt (g) | à = C̃ · organ wt (MBq-h) | SD for à (MBq-h) | τ (h) | SD τ (h) |
|---|---|---|---|---|---|---|---|---|
| Adrenals | 1 | 1.929 | 0.339* | 16.3 | 0.031 | 0.006 | 0.001 | 0.0002 |
| Brain | 1 | 0.229 | 0.040* | 1420.0 | 0.325 | 0.057 | 0.009 | 0.0015 |
| LLI | 4 | 1.060 | 1.053 | 143.0 | 0.152 | 0.151 | 0.004 | 0.0041 |
| Stomach | 3 | 2.178 | 0.654 | 260.0 | 0.566 | 0.170 | 0.015 | 0.0046 |
| Blood | 11 | 1.136 | 0.198 | 454.0 | 0.516 | 0.090 | 0.014 | 0.0024 |
| Heart wall | 10 | 1.195 | 0.348 | 316.0 | 0.378 | 0.110 | 0.010 | 0.0030 |
| Kidney | 3 | 5.192 | 1.819 | 299.0 | 1.552 | 0.544 | 0.042 | 0.0147 |
| Liver | 6 | 6.165 | 1.641 | 1910.0 | 11.774 | 3.134 | 0.318 | 0.0847 |
| Lung | 11 | 0.572 | 0.157 | 1000.0 | 0.572 | 0.157 | 0.015 | 0.0042 |
| Pancreas | 2 | 2.368 | 1.586 | 94.3 | 0.223 | 0.150 | 0.006 | 0.0040 |
| Marrow | 11 | 7.696 | 2.272 | 1120.0 | 8.620 | 2.545 | 0.233 | 0.0688 |
| Spleen | 5 | 1.768 | 0.839 | 183.0 | 0.324 | 0.153 | 0.009 | 0.0041 |
| Bladder† | ||||||||
| Voiding scenario 1 | 5 | 61.622 | 45.700‡ | 211.0 | 13.002 | 9.641 | 0.351 | 0.2606 |
| Voiding scenario 2 | 25.589 | 5.399 | 0.146 | |||||
| Testes | 3 | 1.360 | 0.753 | 39.1 | 0.053 | 0.029 | 0.001 | 0.0008 |
| Remainder§ | 0.872 | 0.160 | 66234.3 | 57.755 | 10.473 | 1.561 | 0.2831 |
↵* SD for organs with only 1 curve were calculated in proportion to SD of remainder.
↵ † Bladder average and SD of 5 patients.
↵ ‡ SD for bladder was calculated from 5 patients with bladder curves.
↵ § Remainder of body for 73.7-kg man. Both voiding scenarios yield same remainder values.
wt = weight; LLI = lower large intestine.