TABLE 3

Clinical Biochemistry and Hematology Test Results in Athymic Mice Implanted with MDA-MB-468 Breast Cancer Xenografts and Treated with 111In-DTPA-hEGF

Parameter*Value with the following treatment:
Normal saline111In-DTPA-hEGF
ALT (U/L)16–4018–46
Serum CR (μmol/L)60–6660–78
WBCs (/L)12.4 × 1095.8 × 109
Platelets (/L)1,208 × 109885 × 109
Erythrocytes (/L)8.9 × 10128.2 × 1012
Hemoglobin (g/L)143136
  • * Normal ranges for mice: ALT, 28–184 U/L; WBCs, 5.0 × 109–13.7 × 109/L; platelets, 600 × 109–1,200 × 109/L; erythrocytes, 7.9 × 1012–10.1 × 1012/L; hemoglobin, 110–145 g/L.