Biodistribution of 99mTc-IL-8 in Neutropenic and Normal Rabbits with Turpentine-Induced Abscesses
| Biodistribution | Neutropenic rabbits (n = 3) | Normal rabbits (n = 4) |
|---|---|---|
| Blood | 0.073 ± 0.004 | 0.069 ± 0.004 |
| Muscle | 0.005 ± 0.001 | 0.004 ± 0.001 |
| Abscess | 0.038 ± 0.014 | 0.41 ± 0.05 |
| Lung | 0.10 ± 0.02 | 0.34 ± 0.04 |
| Spleen | 0.38 ± 0.04 | 0.90 ± 0.08 |
| Kidney | 2.32 ± 0.30 | 2.13 ± 0.22 |
| Liver | 0.110 ± 0.024 | 0.080 ± 0.006 |
| Intestine | 0.044 ± 0.008 | 0.025 ± 0.002 |
| Ratio | ||
| Abscess/blood | 0.5 ± 0.2 | 5.9 ± 0.7 |
| Abscess/muscle | 10 ± 5 | 110 ± 10 |
| Target/background | 1.2 ± 0.1 | 15 ± 1 |
Uptake is given as %ID/g. Values are expressed as mean ± 1 SEM.